Piyanan Taweethavonsawat
Chulalongkorn University, Thailand
Title: The efficacy of selamectin in treatment of Ancylostoma ceylanicum experimental infection in cats
Biography
Biography: Piyanan Taweethavonsawat
Abstract
The efficacy of selamectin single tropical dose against adult of Ancylostoma ceylanicum in cats following induced infections was assessed. Twelve cats were each inoculation with 300 infective third-stage larvae of A. ceylanicum. Cats were randomly allocated by egg count into control and treatment groups. The cats in the treatment group were each treated with a spot on selamectin administered topically at recommended label dose rates. The cats in the control group were not treated. Egg counts were performed until the end of the study period and compared for the treated and control groups. No eggs were detected in the treated group of cats within 4 days of treatment and fecal samples from this group remained negative throughout the rest of the study, resulting in a treatment efficacy (egg reduction) of 100% (P<0.0001). The mean egg counts remained high (558±231 eggs per gram) in the untreated control group for the rest of the study period. This study showed that based on fecal egg count reduction, the spot on selamectin given at the recommended dose is highly effective against infection with A. ceylanicum in cats.