Parasitology, Microbiology and Infection Control

Approaches: Parasitic Disease Control

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Control and eventual elimination of human parasitic diseases requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public health response.Recent developments in new diagnostic tools, however, have opened new avenues for a vast improvement in parasite detection. Firstly, a number of newer serology-based assays that are highly specific and sensitive have emerged, such as the Falcon assay screening test ELISA (FAST-ELISA) , Dot-ELISA , rapid antigen detection system (RDTS) , and luciferase immunoprecipitation system (LIPS) . Secondly, molecular-based approaches such as loop-mediated isothermal amplification (LAMP) , real-time polymerase chain reaction , and Luminex  have shown a high potential for use in parasite diagnosis with increased specificity and sensitivity. Thirdly, proteomic technology has also been introduced for the discovery of biomarkers using tissues or biological fluids from the infected host.